When it comes to entrepreneurship-driven regional growth, a few big population centers garner the glamor, whether Boston, Northern California’s Bay Area, Bangalore, or Beijing. This is not mere optics: the large portion of the $50 billion global venture capital pie fueling entrepreneurial growth is concentrated in or near a few big urban regions. Furthermore, mega-cities seem to be natural hotbeds for growth: as just one example, London, with around 10 million people, currently has a 50% greater incidence of high growth firms compared to other UK regions, and a quarter of the high growth firms in the nation overall.