“Born Global” is becoming the new “Born Digital.” Social media and digital platforms giving local start-ups global reach increasingly facilitate “born global” start-ups. The “two guys in a Silicon Valley garage” paradigm is surrendering to cross-border collaborations between “two guys in a Noe Valley garage, three female coders in a Pune office park, and a machinist of indeterminate gender with a 3D printer cluster in Nanjing.”