Since joining Kleiner Perkins in 1980, venture capitalist John Doerr has helped fund Intuit, Amazon, Google, Twitter, and a host of other well-known tech companies. Many of them utilize a goal-setting system Doerr calls “OKR,” for “objectives” and “key results.” His new book, Measure What Matters, contains his explanation for how and why the system works, as well as case studies by leaders who’ve adopted it — including Bill Gates, Larry Page, and Bono. Doerr stopped by HBR to talk about his passion for setting and reaching goals. Edited excerpts of that conversation follow: